7th Annual WML Academic Symposium

Presenter(s): Maryam Unnisa
Title: Flavonoid components of Passion flower extract antagonize various neuroreceptors
Developed under the guidance of Dr. Chris Breivogel , Pharmaceutical Sciences

"Previous study (Breivogel et al., 2012) has reported that passion flower extract helped reduce nicotine withdrawal effects using a rat behavioral model, hence identifying an additional therapy for smoking cessation. The present study attempted to evaluate the activity of compounds found in passion flower extract which include flavonoids such as, isovitexin, vitexin-glucoside, apiin, vitexin, kaempferol and quercetin. The stimulatory and inhibitory effects of these compounds were tested at brain systems which are found to be involved in nicotine addiction. It was observed that the flavonoid constituents of this passion flower extract were active in inhibiting the brain neurotransmission system involved in nicotine addiction effects. "