7th Annual WML Academic Symposium

Presenter(s): Edward Hicks
Title: The Effects of Morphine and Tetrahydrocannabinol on Male and Female Beta-arrestin2 -/- Mice
Developed under the guidance of Chris Breivogel , Pharmaceutical Sciences

Morphine and Tetrahydrocannabinol are known for their antinociceptive and temperature lowering effects in mice via the mu opioid and CB1 cannabinoid receptors. Beta-arrest2 has been shown to regulate the effects of these receptors. The purpose of this study was to determine if there was a difference in response to Morphine and THC between male and female wild and beta-arrest 2 knockout (beta-arrestin2 -/-) type mice.